Drug Prevents Chemo-Related Hearing Loss in Some Children

One side effect of chemotherapy for some children with cancer is hearing loss. According to a new study, the drug sodium thiosulfate can protect the hearing of children with cancer undergoing treatment with the chemotherapy drug cisplatin.

Today, more than 80% of children diagnosed with cancer are alive at least 5 years after diagnosis. Many of these children are considered cancer free. Researchers are now aiming to reduce the long-term side effects that children experience with many cancer treatments. These can include heart or lung problems, cognitive difficulties, infertility, and hearing loss.

The participants in the trial were randomly assigned to receive sodium thiosulfate 6 hours after each cisplatin treatment or to receive only cisplatin. The children in the sodium thiosulfate group were half as likely to experience permanent hearing loss than children who received cisplatin alone, the researchers reported.

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“Sodium Thiosulfate Prevents Cisplatin-Induced Hearing Loss in Some Children was originally published by the National Cancer Institute.”